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NMN Supplement

NMN Supplement: Choosing Wisely and What to Look For


NMN is an exciting supplement with a lot of promise in the longevity and wellness space. Are you trying to decide how to choose an NMN supplement? Are you interested in learning more about NMN supplements and what you should look for when choosing a supplement? 

NMN (nicotinamide mononucleotide) is a naturally occurring compound that can help promote healthy aging. It’s gaining popularity as a supplement due to its potential to offer numerous benefits for longevity. In this post, we’ll explore what to look for in your NMN supplement and how to choose your supplement. 

What is NMN and what is it’s relationship to promoting longevity?


In a nutshell, NMN, or nicotinamide mononucleotide, is a compound that has been shown to play a role in promoting healthy aging.  It is a precursor to NAD+, a molecule that is essential for various biological processes in the body. As we age, NAD+ levels naturally decline (along with everything else), leading to a decrease in energy production and cellular function. This decline is associated with a decline in overall health and an increase in age-related diseases.

By supplementing with NMN, you can replenish NAD+ levels in the body and support optimal cellular function. This, in turn, can promote healthy aging, reduce the risk of chronic disease, increase energy, and improve overall health. 

NMN has been shown to enhance mitochondrial function in clinical trials, which is responsible for producing energy in cells. By boosting mitochondrial function, NMN can help improve energy levels, increase fitness, and support overall vitality.


Furthermore, NMN has been found to activate certain proteins called sirtuins, which are involved in regulating cellular processes associated with aging and longevity. By activating sirtuins, NMN can promote DNA repair, reduce inflammation, and improve cellular resilience.

Is NMN the Same as Vitamin B3? 

NMN is not the same as vitamin B3 (aka niacin); however, it is related to it.

Vitamin B3 is a water-soluble vitamin that is essential for human health. It is found in meats, poultry, fish, nuts, and seeds, and it is also available as a dietary supplement. Vitamin B3 is involved in a variety of metabolic processes, including the synthesis of hormones and other molecules, and is necessary for the proper functioning of the nervous system and metabolism of carbohydrates, fats, and proteins.

On the other hand, NMN is a different form of vitamin B3, essential for the body’s functions, and found in different foods. Both niacin and nicotinamide are important for overall health, but they have slight variations in how they work in the body.

Here’s a Look at the Benefits of Taking NMN Supplements:

  1. Enhanced Energy Levels: NMN boosts mitochondrial function, leading to improved cellular energy production. This can increase stamina and vitality, benefiting physical performance and an active lifestyle.
  2. Antioxidant Effects: NMN acts as an antioxidant, safeguarding cells against oxidative stress-induced damage. This helps reduce inflammation and supports overall cellular well-being.
  3. Improved Cognitive Function: Studies suggest NMN can enhance cognitive abilities, memory, and focus. It may also slow down age-related cognitive decline, contributing to better brain health.
  4. Cardiovascular Health: NMN supplements potentially aid in maintaining cardiovascular health by promoting healthy blood flow, reducing the risk of heart disease, and enhancing cardiovascular function.
  5. Longevity and Aging: By replenishing NAD+ levels, activating sirtuins, and enhancing mitochondrial function, NMN is believed to promote healthy aging and support optimal cellular function, which can contribute to longevity.

How to choose an NMN Supplement

What to look for when choosing an NMN supplement

  1. Understand NMN’s Purpose:
    • Learn about NMN’s potential benefits, such as its role in supporting cellular energy production and its connection to anti-aging.
  2. Quality Brands:
    • Choose well-known and reputable supplement brands that specialize in high-quality NMN products.
    • Look for brands that have a history of transparency and reliability.
  3. Purity and Transparency:
    • Ensure the NMN supplement is free from fillers, additives, and unnecessary ingredients.
    • Check for third-party testing certificates that verify the purity and potency of the product.
  4. NMN Dosage:
    • Research the appropriate NMN dosage based on available scientific literature.
    • Select a supplement that offers the recommended daily dosage in each serving.
  5. Bioavailability:
    • Look for NMN supplements that use forms with enhanced bioavailability for better absorption.
  6. Check for Additives:
    • Carefully read the ingredient list to avoid supplements with unnecessary binders, preservatives, and artificial colors.
  7. Dosage Form:
    • Choose a dosage form that suits your preferences, such as capsules, tablets, or powders.
  8. Research Scientific Evidence:
    • Look for NMN supplements that are supported by scientific research and clinical studies.
  9. Avoid Proprietary Blends:
    • Opt for products that clearly list the exact amount of NMN per serving, avoiding proprietary blends.
  10. Consult a Healthcare Professional:
    • Before starting an NMN supplement regimen, especially if you have pre-existing health conditions, are taking medications, or are pregnant/nursing, consult a healthcare provider.
  11. Customer Reviews:
    • Read reviews from other users who have tried the specific NMN supplement to gauge their experiences.
  12. Price vs. Quality:
    • While price is a consideration, prioritize quality and effectiveness over choosing the cheapest option.
  13. Expiration Date:
    • Check the expiration date to ensure the supplement is fresh and effective.
  14. Possible Side Effects:
    • Research potential side effects or interactions of NMN supplements, and be cautious if you have any underlying health concerns.
  15. Start Slowly:
    • If you’re new to NMN, consider starting with a lower dosage and gradually increasing it as your body adjusts.


When choosing an NMN supplement, there are several important factors to consider. First and foremost, look for a reputable brand that has a proven track record of producing high-quality supplements. A well-established brand is more likely to adhere to strict manufacturing standards and ensure the purity and potency of their product.


No matter what supplement you use always look for third-party testing and certifications. Supplements that have been independently tested for quality and purity are more reliable and trustworthy. Certifications from organizations like NSF International or USP indicate that the product meets certain quality standards.


Another consideration is the brand reputation. Look for a reputable brand that has a proven track record of producing high-quality supplements. A well-established brand is more likely to adhere to strict manufacturing standards and ensure the purity and potency of their product.


By considering these factors, such as price, brand reputation, and third-party testing, you can choose an NMN supplement that is safe, effective, and provides the benefits you’re looking for.

Potential risks and side effects of NMN supplements


While NMN supplements offer numerous potential benefits for longevity and overall health, it’s important to be aware of potential risks and side effects. Though generally considered safe, NMN has not been extensively studied in humans, so its long-term effects are still not fully understood. As with any supplement, it’s recommended to consult with a healthcare professional before adding NMN to your routine.


Some potential risks and side effects of NMN supplements may include gastrointestinal issues such as diarrhea, nausea, or stomach discomfort. These side effects are usually mild and transient, but if they persist or worsen, it’s important to discontinue use and consult with a healthcare professional.


Additionally, because NMN can affect NAD+ levels, there is a theoretical risk that it may interact with medications or underlying health conditions. It’s crucial to discuss with your healthcare provider if you are taking any medications or have any pre-existing medical conditions.


Overall, while NMN supplements hold promise for promoting healthy aging, it’s important to be cautious and make informed decisions about their use. Consulting with a healthcare professional can help ensure that NMN supplementation is safe and appropriate for you.

Top Pick
Elysium Health Signal NMN Supplement Elysium Health Signal NMN Supplement

Promotes healthy metabolic aging by:

  • Increasing levels of the critical coenzyme NAD+ by 40% via the highly efficient precursor NMN
  • Activating sirtuin 3 (SIRT3) to protect and generate new mitochondria to support cellular energy
  • Helping maintain insulin sensitivity, essential to maintaining healthy blood sugar levels, in muscle
  • Supporting vascular health—critical for your athletic endurance 
  • Supporting brown fat thermogenesis, a cellular process that converts sugar and fat into heat to help maintain body temperature and support a healthy metabolism


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